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Propranolol from Inderal tablets is rapidly and completely absorbed from the gastrointestinal tract and undergoes extensive presystemic elimination due to its high hepatic clearance. If Propranolol is taken in combination with other drugs, particularly a thiazide diuretic. Treatment with Propranolol, laboratory determinations should be made at regular intervals. Inderal reduces the energy used by the heart to pump blood around the body, and so reduces the heart's need for oxygen, which means it can also be used in the management of angina. Propranolol may reduce the oxygen requirement of the heart at any level of effort by blocking catecholamine induced increases in the heart rate, low blood pressure and slow heart rate.
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