You may not see any change in your symptoms until then. You take Synthroid with an appetite-suppressant medication. If you are hypersensitive to thyroid hormone. If you are hypersensitive to thyroid hormone. Levothyroxine sodium. Side effects from Synthroid, other than overdose symptoms, are rare. Some foods also can affect how Synthroid is absorbed, such as soybean flour, cotton seed meal, and dietary fiber. Common side effects produced by Synthroid include fatigue, increased appetite, weight loss, heat intolerance, and fever. Synthroid may rapidly swell and disintegrate resulting in choking, gagging, the tablet getting stuck in your throat, or difficulty swallowing.
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